Combination chemotherapy with the outlined programs is used for patients who were initially treated with radiotherapy alone.
Cancer that recurs more than one year after chemotherapy has been given as the initial treatment may be treated with either the same chemotherapy program, an alternative combination high-dose chemotherapy or chemotherapy and radiation therapy followed by bone marrow transplantation.
Progression on initial treatment with chemotherapy or relapse during the first year after chemotherapy may be treated with high-dose chemotherapy or chemotherapy and radiation therapy (depending on the earlier treatment) followed by bone marrow transplantation.
